Blar i forfatter "Hubner, Wolfgang"

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    • Multimodal super-resolution optical microscopy visualizes the close connection between membrane and the cytoskeleton in liver sinusoidal endothelial cell fenestrations 

      Mönkemöller, Viola; Øie, Cristina Ionica; Hubner, Wolfgang; Huser, Thomas Rolf; McCourt, Peter Anthony (Journal article; Tidsskriftartikkel; Peer reviewed, 2015)
      Liver sinusoidal endothelial cells (LSECs) act as a filter between blood and the hepatocytes. LSECs are highly fenestrated cells; they contain transcellular pores with diameters between 50 to 200 nm. The small sizes of the fenestrae have so far prohibited any functional analysis with standard and advanced light microscopy techniques. Only the advent of super-resolution optical fluorescence microscopy ...

    • Primary rat LSECs preserve their characteristic phenotype after cryopreservation 

      Mönkemöller, Viola; Mao, Hong; Hubner, Wolfgang; Heimann, Peter; Levy, Gahl; Huser, Thomas; Kaltschmidt, Barbara; Kaltschmidt, Christian; Øie, Cristina Ionica (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-02)
      Liver disease is a leading cause of morbidity and mortality worldwide. Recently, the liver non-parenchymal cells have gained increasing attention for their potential role in the development of liver disease. Liver sinusoidal endothelial cells (LSECs), a specialized type of endothelial cells that have unique morphology and function, play a fundamental role in maintaining liver homeostasis. Current ...